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doi: 10.1111/exd.12089 [DOI] [PubMed] [Google Scholar] 7.Costin G.E., Hearing V.J.2007
The effects of oral B12 vitamins become visible after a minimum period of 2 to 4 weeks
The peptide is cleaved and released from its parent protein SPARC during the degradation of extracellular matrix, to aid in tissue remodeling by increasing levels of angiogenesis [2]
But the clinical evidence base is thinner than the marketing suggests, and critical questions about skin penetration, optimal formulation, and long-term outcomes remain unanswered
Also, advise of any health or medication changes
