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Reasons for leaky gut can include over the counter or prescription medications, antibiotic use, toxin exposure, hormonal changes, food intolerances, poor diet and others

doi:10.1016/j.cell.2015.06.054 pmid:26232230 Koju N, Taleb A, Zhou J, Lv G, Yang J, Cao X, Lei H, Ding Q (2019) Pharmacological strategies to lower crosstalk between nicotinamide adenine dinucleotide phosphate (NADPH) oxidase and mitochondria

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Pharmacodynamics and pharmacokinetics of Neurobion All three vitamins B1, B6, and B12 play important roles in the normal metabolic processes of nerve cells

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