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Shock 34: 55559 [DOI] [PubMed] [Google Scholar] Zhang Q, Raoof M, Chen Y, Sumi Y, Sursal T, Junger W, Brohi K, Itagaki K, Hauser CJ 2010b

Manganese is a transition metal capable of oscillating between several oxidation states which makes it suitable for the accommodation of superoxide radical anion and the design of SOD mimetic compounds (Vincent et al

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Importantly, these patients do not exhibit severe immunodeficiency ( This unique clinical phenotype strongly supports DPP1 inhibition strategy feasibility, indicating that even with severely reduced NSP activity, overall immune defense function can remain essentially intact

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