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Definition of a tolerable upper intake level of niacin: a systematic review and meta-analysis of the dose-dependent effects of nicotinamide and nicotinic acid supplementation

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However, despite being devoid of LDH and counterscreen activity, this peptide showed a narrow therapeutic index ( ~ 20-fold) with proliferation potencies of 1.5 and 31 M in HCT116 and Ca Ski, respectively (Fig

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