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It was found that melatonin may protect against ischemia-reperfusion injury by activating silent information regulator 1 (SIRT1) signaling in a receptor-dependent manner [21]

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Pathogenesis Clostridium tetani produces the exotoxins tetanolysin (a haemolysin) which may enhance tissue invasion and tetanospasmin (a neurotoxin) which is plasmid-coded and responsible for the signs of tetanus

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RNA-dependent RNA polymerases from flaviviruses and Picornaviridae
