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At MOI 1, the viability was approximately 90% at 3 hpi, decreasing to 44.2% at 6 hpi, where observing CPE was already possible

These carotenoids inhibit melanin synthesis which naturally results in a lightened skin tone and decrease in melasma

SLC38A1 and SLC38A2 SLC38A1 (SNAT1) and SLC38A2 (SNAT2) are sodium-dependent neutral amino acid transporters that drive glutamine influx into cells 90

doi: 10.1089/ars.2009.2683
