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Description
In EGF-stimulated CRC cells, fidarestat potentiated EGF-induced Nrf2 and upregulated the expression of peroxisome proliferator-activated receptor gamma coactivator (PGC)-1alpha, transcription factor A, mitochondrial (TFAM), and COX-IV and attenuated DNA damage as seen by decreased levels of 8-hydroxy-2'-deoxyguanosine
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Drug Categories Research peptides, Regenerative therapeutics (investigational) Additional Notes Summary Table Disclaimer For Research Use Only
doi: 10.1124/pr.108.000869 110 VillanuevaIAlva-SnchezCPacheco-RosadoJ
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