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20 kg: 55 mL/m 2 (provides 5.5 g/m 2 of sodium phenylacetate and 5.5 g/m 2 of sodium benzoate) IV loading dose, then can follow with maintenance dose, as above

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With research interests covering nearly aspect of pediatric cancer care, our work is making great advancements in childhood cancer.

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Considerations in selecting the drug refer to several studies, one of which is a study by Hassan et al, which states that acyclovir could be interfere with the replication of HSV virus DNA with the help of the thymidine kinase enzyme will change the genetic code of the virus so that it produces false nucleotides with result in inhibition of HSV virus DNA synthesis