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Research demonstrates bidirectional gut-brain communication: peripheral BPC-157 administration increased brain serotonin synthesis, produced antidepressant effects, and prevented brain lesions in intestinal resection models

However, levels may be depleted by poor diet, pollution, toxins, stress, ageing and infections

Intracellular compartmentation, structure and function of creatine kinase isoenzymes in tissues with high and fluctuating energy demands: the phosphocreatine circuit for cellular energy homeostasis