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56 Microvesicles from MM patients have also been found to express functional adenosinergic ectoenzymes that can produce ADO from ATP and NAD + , 57 while treatment in vivo with daratumumab can induce the release of microvesicles expressing CD38, among other molecules such as CD39, CD73, CD203a, PDL1, CD55, and CD59

The sequence was found to remove S oligomers, as monitored via SEC, and the formation of a single monomeric peak was observed after four days of incubation