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[177] In a 2001 study by Rivers et al., [178] it was shown that an absolute and relative reduction in mortality from sepsis can be reduced 16 percent and 30 percent, respectively, when aggressive care is provided within six hours of hospital arrival

Similarly, essential oils from Citrus lemon also offered significant gastroprotection linked to increased mucus secretion, vasoactive intestinal peptide (VIP), and prostaglandin E2 (PGE2) levels rather than modulation of mucosal redox factors [51]

Together, these currently preliminary observations raise the possibility that redox signaling functions in interorganellar and intercellular ways between the redox factories of eukaryotic cells: mitochondria, peroxisomes and the ER

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