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While this review primarily focuses on the well-characterized receptor-mediated signaling pathways, it is crucial to first acknowledge that at high pathophysiological concentrations, certain hydrophobic secondary BAs, such as deoxycholic acid (DCA), can exert direct cytotoxic effects on cancer cells, which may complement their immunomodulatory roles
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[DOI] [PMC free article] [PubMed] [Google Scholar] 77.Corchero J., Manzanares J., Fuentes J.A
Metabolic flux analysis HGC27 cells were cultured in complete RPMI-1640 media supplemented with or without 10 ng/mL TGF1 for 6 h
Free Radical Biology and Medicine 37, 1995-2011CrossRefGoogle ScholarPubMed 147Ramsey, C.P., Glass, C.A., Montgomery, M.B
