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Most patients neglect early symptoms and receive inadequate treatment, leading to a continuous deterioration of their condition

The foundational evidence is a 2017 Cell study in aged and progeroid mice , where FOXO4-DRI reduced senescent-cell burden and restored markers such as fur density and renal function [3]

US20250018019A1

Blocking autophagy in oligodendrocytes limits functional recovery after spinal cord injury
