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This formulation is provided as a pre-standardised research solution to support consistent peptide composition, controlled handling, and reproducibility across non-clinical laboratory workflows

No long-term adverse effects were reported among the participants in follow-up as long as 55 months

There is no official contraindication between creatine and tirzepatide, and no documented drug interaction exists in FDA labeling or major drug databases

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The selection of the transgenic 5xFAD mouse model in our study was based on its ability to recapitulate an AD-like phenotype achieved through the expression of APP and PSEN1 transgenes (Brody et al., 2017