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Burgi, ACS Applied Nano Materials 1, (2018) 42584267

Hepatic metabolism contributes to BPC-157 clearance, though the peptide does not appear to undergo extensive first-pass metabolism that would completely prevent oral bioavailability

Copper compounds are also used as actives or excipients in cosmetic and pharmaceutical products, e.g., copper peptide for skin regeneration purposes, cupric aspirinate and cupric salicylate for rheumatoid arthritis treatment, copper conjugated dendrimer for anti-tumoral activity, and copper liposome for enhanced stability of doxorubicin 5,6,7,8,9

However, emerging research protocols are now investigating secondary mechanisms that could position this extract as a complementary therapeutic agent alongside conventional diabetes medications, potentially enhancing patient outcomes through synergistic effects

The role of redox homeostasis in tumor progression: implications for cancer therapy