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Dev, S., et al
doi: 10.1016/j.tplants.2005.11.002 108 MittlerR.ZandalinasS
Clinical studies further confirm a moderate to strong association between oral H.p infection and higher caries severity, specifically manifested as higher DMFT/DMFS scores, ICDAS II code 6 lesions, and an increased number of affected teeth (Hamada et al., 2019
Investigators have described this pattern as a "broad reset" of pathways associated with cellular aging language that, while evocative, remains pre-clinical and has not been translated into validated human therapeutic claims
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