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[DOI] [PubMed] [Google Scholar] 234.Rubinsztein DC

Hepatic Impairment As with many other medications, use a lower or less frequent dosage in patients with hepatic impairment [see Clinical Pharmacology (12.4) and Use in Specific Populations (8.6)]

H., Bi, C., & Holick, M

However, these mechanisms are not flawless

Microneedle delivery can also significantly increase the local concentration of drugs and enhance therapeutic efficacy
