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The explanation for that could be due to the noticeable increase in oxidative stress in the testicular tissue, causing Leydig cell destruction

About Obesity | World Obesity Federation

Journal of Drug Delivery Science and Technology, 75 , Article 103654
( 10.1186/s12872-019-01310-5) [DOI] [PMC free article] [PubMed] [Google Scholar] 11

In spite of this, decreases in omega-6 fatty acid levels were observed in our study, as previously reported, which support the usefulness of EPA administration
