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Supplementing with selenium can help enhance the phagocytic and bactericidal capabilities of these cells, thereby improving nonspecific immune function [128,129]

Under the guidance of the spleen-kidney correlation theory, exploration into the modern mechanisms underlying Yishen Huashi granules in treating RF has revealed that it can increase the intestinal flora content, such as Lactobacillus and Lactobacillus murinus , as well as serum metabolites such as phosphatidylethanolamine through the "gutkidney axis", thereby regulating the expression of mRNAs such as Adcy3 in the kidney and adjusting pathways related to glucose and lipid metabolism to improve DN [177]

3320, Journal articles | 2018 McVey BFP

In Vivo investigation Animals The current investigation utilized adult male SpragueDawley rats weighing 150200 g

Investigations into the mechanisms behind the increased intestinal permeability in animal models have focused on expression of the TJ proteins