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[DOI] [PMC free article] [PubMed] [Google Scholar] 15.Danelon V., Garret-Thomson S.C., Almo S.C., Lee F.S., Hempstead B.L

Inactivation of the HIF-1/PDK3 signaling axis drives melanoma toward mitochondrial oxidative metabolism and potentiates the therapeutic activity of pro-oxidants

It also supports the regeneration of other antioxidants, such as vitamins C and E

Further large animal experiments and pharmacokinetic studies are needed for validation (209)

Melanopsin phototransduction: beyond canonical cascades
