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Daily stress, poor diet, and lack of sleep are "withdrawals." Supplementation and healthy habits are "deposits." If you are constantly making withdrawals without any deposits, you eventually run into a deficit, which manifests as fatigue and poor sleep

These symptoms may suggest inadequate B12 replacement, concurrent iron or folate deficiency, or alternative haematological conditions requiring investigation

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The major turning point for me was the holiday season of 2014

Table 1 Summary of the bacterial proteins that interact with platelets either through direct interactions, released toxins, or via bridging plasma proteins