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Acetyl CoA carboxylase inhibition reduces hepatic steatosis but elevates plasma triglycerides in mice and humans: a bedside to bench investigation
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Retatrutide, a GIP, GLP-1 and glucagon receptor agonist, for people with type 2 diabetes: a randomised phase 2 trial
Trial dose range: 112mg, once weekly, subcutaneous Standard escalation: 2mg +2mg every 4 weeks 12mg (~20 weeks) Pharmacokinetics: half-life ~6 days
