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As revealed by RP-HPLC/MALDI-TOF analysis, treatment of 1.2 M M pro with 2 mM GSSG led to an estimated 45% monoglutathionylation (only an estimate based on the mass abundances), whereas treatment with 10 mM GSSG led to mono- (11%), di- (50%), and tri-glutathionylation (35%), with less than 4% of M pro remaining unmodified (Figure 1C)
It included mainly males (75%) with persistent negative symptoms
10.1111/jpi.12661 137
