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SIRT6 helps maintain stable telomeres, which directly influences how cells age [10]

Aust J Zool 26:699712 Kirsten E, Sharma ML, Kun E (1978) Molecular toxicology of ()-erythro-fluorocitrateselective inhibition of citrate transport in mitochondria and binding of fluorocitrate to mitochondrial proteins.15

Nutrients 10(12):1924

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Notably, some PKM2 translocates into the nucleus, where it collaborates with HIF-1 to activate genes for the IL-1 precursor and components of the NLRP3 inflammasome