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Description
They are phagocytosed by macrophages as foreign particles and recognized by Toll-like receptors 2 and 4 (TLR2/TLR4), which subsequently activate and oligomerize the NLRP3 complex

In hypoxia reduced expression of EAAT1 and 2 contributes to increase extracellular glutamate concentration leading to neuronal overexcitation and excitotoxicity (Rossi et al., 2007

Hardan et al

doi: 10.3390/molecules23092401 138 WangPLiuYKangSYLyuCHanXHoTet al

We also examined whether expression of Dnmt contributes to global and gene-specific methylations, which alter the expression of vitamin D metabolism genes
