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Description
OCTN2 is a unique transporter with a dual-mode of transport as both Na + -independent organic cation transporters and Na + -dependent and high-affinity carnitine transporters [57]
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Interestingly, these overgrowths can be found in conditions as varied as Hashimotos, irritable bowel syndrome, restless leg syndrome, and even autism spectrum disorder (ASD)
they share the common properties of increasing brain glutamate concentration and neurotransmission and of activating rCMRglc in frontal areas and subcortical aminergic nuclei (Toth et al., 1993
McCaffery and Deutsch, 2005)
