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Once in the cytoplasm, intracellular thioesterases rapidly convert SAG to GSH

In the rat retina, IGF-1 can induce retinal ganglion cell (RGC) survival and axon growth by activating phosphatidylinositol 3-kinase (PI3K) and mitogen-activated protein kinase (MAPK)/extracellular-signal regulated kinase (ERK) pathways (Dupraz et al., 2013

Punicalin, an agent used to treat hepatitis B virus (HBV), was identified as a possible PSTK inhibitor that exhibited synergistic efficacy when applied together with Sorafenib to treat HCC in vitro and in vivo (Chen Y

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This synthesis method produced nanoparticle with long-term stability without any sign of agglomeration (Boca et al., 2011)