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Efficacy of MUCIPLIQ on the incidence of radio-chemotherapy-induced mucositis in patients suffering from oral cancer (MUCIPLIQ)

Although the pKa value of Cys-thiol GSH is relatively high (8.99.4) [3], indicating low reactivity in the intracellular environment, its central role in protecting cells from reactive oxygen/nitrogen species (RONS) is based on enzyme-catalyzed reactions, efficient recycling pathways, as well as the mass effect achieved by its high intracellular concentrations (210 mM)

R.GenovesiD.LeddaA.VinciguerraG.RicciA.et al (2008)