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Importantly, in active intestinal inflammation, HIF-2 may exert context-dependent effects on ferroptosis susceptibility: even under systemic iron deficiency, local inflammatory cues can paradoxically enhance epithelial iron uptake and/or perturb subcellular iron distribution, thereby increasing the labile iron pool and promoting lipid peroxidation

Hoffmann G, Aramaki S, Blum-Hoffmann E, Nyhan WL, Sweetman L

There may not be a lot you can do to reduce your exposure to persistent environmental toxins

Even though this condition is harmless, it may be upsetting for some people

"Beyond aerobic glycolysis: transformed cells can engage in glutamine metabolism that exceeds the requirement for protein and nucleotide synthesis"
