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Emodin-loaded polymer lipid hybrid nanoparticles (E-PLNs) exhibited superior anti-cancer efficacy against breast cancer (MCF-7) cells by enhancing uptake, promoting early apoptosis via Bax/Bcl-2 pathway, and inhibiting tumor growth by over 60% in mice

Research suggests that mTOR acts as a growth-control switch that regulates cell division and migration

The phenotype was initially associated with a differential sensitivity to red/far red light, suggesting the involvement of a differential phytochrome-light perception and the classification of the line as a photomorphogenic mutant (Kendrick et al., 1997)

Our findings revealed that Gstp gene knocked caused a significant increase in mouse serum HMGB1 level, suggesting that GSTP might function as a negative regulator in controlling HMGB1 release in sepsis

Metabolic flexibility and nutrient addiction are critical for cell fate determination