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THE TARGET CONCENTRATION APPROACH TO DESIGNING A RATIONAL DOSAGE REGIMEN A rational dosage regimen is based on the assumption that there is a target concentration that will produce the desired therapeutic effect

BPC 157 promotes VEGFR2 internalization in association with VEGFR2-Akt-eNOS activation without the need for other known ligands or shear stress [94]

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Another proposed mechanism involves the regulation of inflammatory cascades
