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H3K9me3 and H3K27me3 histone marks promote heterochromatin formation, reinforcing senescence-associated gene silencing.21 Senescent cells also exhibit DNA methylation changes, altering gene expression patterns.22 Senescence in Aging and Age-Related Diseases The role of cellular senescence in aging is multifaceted

Cutaneous wounds are at higher risk of aberrant collagen deposition and impaired remodelling, which can result in hypertrophic scars and keloids

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(1981) Mitochondrial respiratory capacity and Na + - and K + -dependent adenosine triphosphatase-mediated ion transport in the intact renal cell