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Accumulation of HIF-1 has been identified in persistent pathofibrogenesis and may play a role in progression of systemic sclerosis (SSc), an inflammatory autoimmune disease resulting in abnormal fibroblast activation and fibrosis leading to skin thickening and organ insufficiency

central compartments, but insufficient information limits firm conclusions at this point

doi: 10.1016/j.ijpx.2021.100087 163

erinaceus yielded mainly heteropolysaccharides along with glycoproteins ( H

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