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189 A trispecific Tcell engager antibody, SAR442257, has also been developed that simultaneously binds to CD3, CD28, and CD38, and is in Phase 1 investigation

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(e) cross-sectional studies with no time restriction, (f) only studies published in English were included due to resource limitations and to ensure accuracy in data extraction and risk-of-bias assessment

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Therefore, human plasma TdR level does not appear to be a useful PD phenotypic marker for TS inhibition

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