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Description
Chromosome four disomy is the second most prevalent aneuploidy that results in azole heteroresistance, and it is mostly caused by three genes: GLO3 and GCS2 , which encode ADP-ribosylation factor proteins, and SEY1 , which encodes a GTPase

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Dermatological effects: Less frequently, patients may experience mild skin reactions, such as a temporary rash or pruritus (itching)

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Shah, Giuseppe Curigliano