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This article demonstrates that conjugation of electrophilic cyanoenone compounds and KEAP1 is selective and reversable

each R B is independently H or OR D , where R D is Q 1 Q A_ Q 2_ T, a bioreversible group, or a non-bioreversible group

Extensive research has established glutathione peroxidase 4 (GPX4) as a critical regulator in the pathogenesis of multiple pathological conditions, including osteoarthritis 35 ,cancers 47 , and liver disease 48

research in the field of artificial intelligence technology