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There are two distinct glutaminase genes in humans identified as GLS (encoding the GLS1 enzyme) and GLS2 (encoding the GLS2 enzyme)
doi: 10.2174/0113894501312703240826070530 188
Biochimica Et Biophysica Acta (BBA)-Molecular Cell Research 1870:119381 Lukcsi S, Munkcsy G, Gyrffy B (2024) Harnessing hyperthermia: molecular, cellular, and immunological insights for enhanced anticancer therapies
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Similar to GCLC, c-Myc also induced the human GCLM promoter activity under H 2 O 2 -induced stress (Benassia et al., 2006)
