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However, during an initial loading phase, a more frequent schedule may be necessary

It should not be co-administered with drugs that are known to be strong CYP2C19 inhibitors, such as voriconazole and fluvoxamine

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Many patients initially dismiss these signs, attributing them to a busy lifestyle

The AOD 9604 trials did not report responder rates in the same way, but the modest average effect suggests a much lower percentage of participants experienced noticeable changes