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MTHFR protein exists as a homodimer comprising two N-terminal catalytic domains with binding sites for NADPH, methylene-THF, and cofactor FAD-linked to the regulatory domain (C-terminus) (Figure 2B)

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2024;12:e17302

[DOI] [PMC free article] [PubMed] [Google Scholar] Trigwell S.M., Lynch P.T., Griffin M., Hargreaves A.J., Bonner P.L.R
The accumulated GSH is divided between the daughter cells, in which the process begins again
