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Therefore, ApisTox can serve as a part of benchmarks for novel classification algorithms, including out-of-distribution testing of models designed using medicinal chemistry data
Cialdella-Kam L, Nieman DC, Sha W, Meaney MP, Knab AM, Shanely RA (2013) Dose-response to 3 months of quercetin-containing supplements on metabolite and quercetin conjugate profile in adults

Treatment with CoPP (Cobalt Protoporhyrin), a synthetic analog of heme that induces HO-1 without competing for its catalytic site, led to upregulation in both basal (Figure 2A) and post-IRI HO-1 mRNA levels (Figure 2B) that led to decreased IRI overall, evidenced by decreased post-IRI serum transaminases

Karimov M, Schulz M, Kahl T, Noske S, Kubczak M, Gockel I, et al
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