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Furthermore, ligands derived from the hexapeptide Ang IV but that are not proven to act as IRAP inhibitors have been reported

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It is a membrane stabilizer and counteracts gut-leaky syndromehas profound cytoprotective activityand specifically [controls] the VEGF [vascular endothelial growth factor] and NO [nitric oxide] pathways, in particular the prostaglandin pathway (Sikiric et al, 2022)
