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It is likely that such commonality in the responses, with diverse noxious events [8,9,10,11,12,13,14,15,16,17,18,19,20,21,22,23,24,25] (as the cytoprotection concept posits for cytoprotective agents [35,36]), can suggest the equal efficacy of this therapy that should be demonstrated in the later course as well [6,30,31,32,33,34]