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Description
Creatine synthesis: hepatic metabolism of guanidinoacetate and creatine in the rat in vitro and in vivo
If so, you may be deficient in vitamin B12
The following databases were searched: Ovid MEDLINE, MEDLINE In-Process and Other Non-Indexed Citations, Ovid Embase, Wiley Cochrane, EBSCO Cumulative Index to Nursing & Allied Health Literature (CINAHL), and Centre for Reviews and Dissemination/International Agency for Health Technology Assessment
It benefits nutrient absorption, metabolism, brain function, and more

And the benefits go far beyond just addressing deficiencies
