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14a, b)
FBXW7 contributes to circadian rhythmicity by targeting mTOR, a key regulator of circadian translation, for ubiquitin-mediated degradation, resulting in opposing oscillations between FBXW7 and mTOR protein levels and enabling rhythmic control of translational output (Okazaki et al., 2014
the volume gets amplified and turned up putting the nervous system into overdrive
The life and times of endogenous opioid peptides: Updated understanding of synthesis, spatiotemporal dynamics, and the clinical impact in alcohol use disorder
IECs are rapidly renewed and replaced every couple of days 12,13
