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The SEMA domain of the transmembrane chain facilitates interaction by binding to HGF, with additional stabilization provided by the PSI domain [9, 17, 18]

Jonathan S, Johanne B-W, Lauren B, Amit N P, Matthew J, Charlotte L et al

doi: 10.1073/pnas.141224798

Grndemann suggested naming OCTN1 the ergothioneine transporter (ETT) to reflect its predominant biological role

Figure 5 The generation of ROS by mitochondria is highly dependent upon mitochondrial membrane potential (m) and the amount of ROS produced can either trigger cellular proliferation (low ROS) or apoptosis (high ROS) (Martinez-Reyes and Cuezva, 2014)