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For example, zinc is vital for protein synthesis, gene expression, and cell signaling (Rayman, 2012)

Sumoylation is involved in various cellular processes, including DNA damage repair, cell cycle progression, apoptosis, immune response, and epigenetic induction or repression of certain genes

Notably, two tryptophan metabolites, indolepropionate and indolelactate and produced by gut microflora (Clostridum sporogenes specifically) (Wikoff et al., 2009
