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Under the if-all-adhere estimand, CagriSema produced 23.0% weight loss at 84 weeks, against 25.5% for tirzepatide
126,143,144 However, drugs in these classes remain first-line treatment for depression

Conclusion Vitamin B12 supplementation is most effective for treating specific deficiencies, while B complex supplementation may offer broader metabolic and health benefits, particularly in certain populations such as pregnant women, individuals with diabetes, or those seeking improved physical performance
