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Furthermore, ageing has been linked to dysregulated metabolic homoeostasis and remodelling of metabolism in immune cells 167

[15] Lu, S.C

However, it is presently unclear whether NRF1 or other transcription factors involved in mitobiogenesis directly affect the expression of Bnip3

Because exosomes from a particular cell type provide sets of biomolecules exclusive to that cell, exosomes have been viewed as miniature replicas of their parent cells

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