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Certain CYP isoformsnotably CYP2E1are potent sources of ROS, especially upon induction (e -TrCP promotes glycogen synthase kinase 3-dependent degradation of the Nrf2 transcription factor in a Keap1-independent manner

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Further research and clinical studies are needed to evaluate the performance of this GSH-based modification in fat transplantation

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USA 91 , 76087612 (1994)

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doi: 10.1089/jir.2014.0210 20 NorthR

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RAS-selective lethal 3 (RSL3) inhibits GPX4 by covalently binding to it, leading to lipid peroxide accumulation and ferroptosis induction

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