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77,78 The extracellular and intracellular cystine and glutamate concentrations keep the function of system Xc to protect cells in an antioxidant state

Sanchez JF

doi:10.1155/2015/487160 VeDA

A simple covert hepatic encephalopathy screening model based on blood biochemical parameters in patients with cirrhosis

however, it requires hepatic transformation to its active metabolite via CYP2D6, resulting in unpredictable pharmacokinetics in patients with liver disease
